Preventing pathological expansion of tandem repeats
Analysis of the FGF14-SCA27B repeat locus identifies a common 5'-flanking insertion that is present exclusively in non-pathogenic alleles and enhances repeat stability.
Analysis of the FGF14-SCA27B repeat locus identifies a common 5'-flanking insertion that is present exclusively in non-pathogenic alleles and enhances repeat stability.
A new single-cell multiomic technique, GAGE-seq, pushes the frontier of single-cell 4D genome analysis by enabling analysis of rare cell populations in complex tissues.