Bioorganic & Medicinal Chemistry Letters presents preliminary experimental or theoretical research results of outstanding significance and timeliness on all aspects of science at the interface of chemistry and biology and on major advances in drug design and development. The journal publishes preliminary communications in camera-ready form in much the same format as Tetrahedron Letters and strives to provide maximum dissemination to a large, international audience, the outstanding advances in bioorganic chemistry, bioinorganic chemistry and related disciplines. From 1996, Bioorganic & Medicinal Chemistry Letters is included in Tetrahedron Alert, the first phase of the Tetrahedron Information System. Tetrahedron Alert is the new electronic information service accessible via the Internet, and is a pre-publication service which provides the contents lists and graphical abstracts of current and forthcoming issues for all 5 of the Tetrahedron journals. Updated weekly Tetrahedron Alert offers: the option to view the contents list as graphical abstracts; the ability to search a single journal or across all 5 journals; search options using user-friendly query forms; hypertext links to facilitate navigation; the facility to print to your own printer. At any given time, Tetrahedron Alert contains approximately 3-4 months worth of current issues and accepted papers. A sampler which demonstrates the content and functionality of Tetrahedron Alert can be accessed via the Tetrahedron Information System Home Page at http://www.elsevier.nl/locate/tis.