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Diacylglycerol acyltransferase inhibitory new meroterpenes from the seeds of Psoralea corylifolia, and their structure-activity relationship study

期刊: FITOTERAPIA, 2021; 151 ()

Five new meroterpenes, 12 alpha-Psoracorylifol F (1), 7 beta,8 alpha-hydroxy-12 beta-Psoracorylifol F (2), 8-ketone-Cyclobakuchiol C (3), 7 alpha,8 be......

Chisosiamens A-E, five new ring-intact limonoids with isomerized furan ring from the fruit of Chisocheton siamensis

期刊: FITOTERAPIA, 2021; 151 ()

Five new ring-intact limonoids with isomerized furan ring, chisosiamens A-E (1-5), along with four known compounds (6-9) were isolated from the fruit ......

Polyprenylated acylphloroglucinol meroterpenoids with PTP1B inhibition from Hypericum forrestii

期刊: FITOTERAPIA, 2021; 153 ()

Three new polyprenylated acylphloroglucinol meroterpenoids, hyperiforins A-C (1-3), were isolated from Hypericum forrestii (Chittenden) N. Robson, tog......

Coumarin-based derivatives with potential anti-HIV activity

期刊: FITOTERAPIA, 2021; 150 ()

Acquired immunodeficiency syndrome (AIDS), as a result of human immunodeficiency virus (HIV) infection which leads to severe suppression of immune fun......

alpha-Tomatine, a novel early-stage autophagy inhibitor, inhibits autophagy to enhance apoptosis via Beclin-1 in Skov3 cells

期刊: FITOTERAPIA, 2021; 152 ()

Targeting the autophagy process is considered to be a promising new strategy for drug treatment of ovarian cancer. alpha-Tomatine, a steroidal alkaloi......

Isoangustone A induces autophagic cell death in colorectal cancer cells by activating AMPK signaling

期刊: FITOTERAPIA, 2021; 152 ()

Phytochemicals, especially flavonoids, have been widely investigated for their diversified pharmacological activities including anticancer activities.......

Discovery of cyclooxygenase-2 inhibitors from Kadsura coccinea by affinity ultrafiltration mass spectrometry and the anti-inflammatory activity

期刊: FITOTERAPIA, 2021; 151 ()

The medicinal plant Kadsura coccinea distributing in South China, was widely used for reducing inflammation and relieving pain. Previous study in our ......

Four new phenanthrene derivatives from Bulbophyllum retusiusculum

期刊: FITOTERAPIA, 2021; 152 ()

Three new dihydrophenanthrenes, retusiusine D (1), retusiusine E (2), retusiusine F (3), and a new phenanthrene retusiusine G (4), together with two k......

Highly modified nor-clerodane diterpenoids from Croton yanhuii

期刊: FITOTERAPIA, 2021; 153 ()

Phytochemical investigation of the leaves and twigs of Croton yanhuii led to the isolation of seven highly modified nor-clerodane diterpenoids (1-7), ......

Phloroglucinol-derived lipids from the leaves of Syzygium cumini and their neuroprotective activities

期刊: FITOTERAPIA, 2021; 153 ()

Based on the typical HPLC-UV-MS profiles and characteristic 1H NMR signals, twelve new phloroglucinol-derived lipids (1-12), featuring a long linear a......

Sesquiterpenoids and a steroid from the algicolous Trichoderma brevicompactum

期刊: FITOTERAPIA, 2021; 153 ()

Six new sesquiterpenoids including three bisabolane derivatives, trichobisabolins O-1, O-2, and P (1-3), two nerolidol derivatives, trichonerolins A a......

Five new secondary metabolites from the fungus Phomopsis asparagi

期刊: FITOTERAPIA, 2021; 150 ()

Five new compounds, including a pair of diphenylcyclopentenone enantiomers (+/-)-phomopsisin A (1), a sesquiterpenoid 15-hydroxylithocarin A (2), a ne......

New sterols from the South China Sea sponges Halichondria sp.

期刊: FITOTERAPIA, 2021; 152 ()

A detailed chemical investigation of two specimen of South China Sea sponges Halichondria sp. (No. 19-XD-47 and No. 17-XD-87) have resulted in the iso......

Diterpenoids from the seeds of Euphorbia lathyris and their effects on microglial nitric oxide production

期刊: FITOTERAPIA, 2021; 150 ()

Four new lathyrane-type diterpenoids (1-4) and a novel macrocyclic diterpenoid (5) featuring a 5/7/7/4-fused ring system, together with seventeen know......

Cytotoxic guaianolides and seco-guaianolides from Artemisia atrovirens

期刊: FITOTERAPIA, 2021; 151 ()

A phytochemical investigation of a medicinal plant Artemisia atrovirens was carried out, resulting in the characterization of a novel bis-nor seco-gua......

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