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The involvement of ERK1/2 and p38 MAPK in the premature senescence of melanocytes induced by H2O2 through a p53-independent p21 pathway

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 105 (2)

Background: The pathogenesis of vitiligo is still unknown and oxidative stress is an important factor that can damage or incapacitate melanocytes. Obj......

JIF:3.14

MiR-155 inhibits TP53INP1 expression leading to enhanced glycolysis of psoriatic mesenchymal stem cells

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 105 (3)

Background: Psoriasis is a systemic disease with multiple associated comorbidities, including metabolic syndrome. Studies suggest that chronic inflamm......

JIF:3.14

MicroRNA-486-3p promotes the proliferation and metastasis of cutaneous squamous cell carcinoma by suppressing flotillin-2

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 105 (1)

Background: Dysregulation of miR-486-3p was related to the growth and development of a variety of cancers, but the specific function of miR-486-3p in ......

JIF:3.14

IL-33/ST2 axis contributes to the dermal fibrosis of systemic sclerosis via promoting fibroblasts activation

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 107 (2)

Background: Systemic sclerosis (SSc) is a chronic immune-mediated rheumatic disease that is characterized by fibrosis of the skin and internal organs.......

JIF:3.14

Qa-1b functions as an oncogenic factor in mouse melanoma cells

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 105 (3)

Background: Malignant melanoma is one kind of rare cancer in human and animals, which occurs not only in skin but also in the mucous membranes of the ......

JIF:3.14

DNA methylation markers in peripheral blood for psoriatic arthritis

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 108 (1)

Background: The clinical manifestations of psoriatic arthritis (PsA) are highly heterogeneous and no reliable diagnostic biomarkers exist.Objective: W......

JIF:3.14

Photo-aging evaluation- In vitro biological endpoints combined with collagen density assessment with multi-photon microscopy

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 105 (1)

Background: Ultraviolet exposure has profound effect on the dermal connective tissue of human skin. Objective: We aimed to develop and validate an eva......

JIF:3.14

The c.323 G > C mutation in LORICRIN causes new-found late-onset autosomal dominant loricrin keratoderma in a Chinese Han Pedigree

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 106 (1)

Background: Loricrin keratoderma is a rare early-onset autosomal dominant skin disorder. At present, no clinical reports have been published on charac......

JIF:3.14

E3 ubiquitin ligase Trim33 ubiquitylates Annexin A2 to promote NF-Kappa B induced skin inflammation in psoriasis

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 107 (3)

Background: Tripartite motif-containing protein 33, a member of the TRIM E3 ligase family, is shown to be involved in tumorigenesis, cell proliferatio......

JIF:3.14

through the HPA axis

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 106 (3)

Background: Clinical findings have shown that skin depigmentation disorder such as vitiligo may be closely associated with the release of central and ......

JIF:3.14

Tiamulin inhibits TNF-? and alleviates psoriasis-like dermatitis

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 107 (1)

Background: TNF-alpha elicits a cascade amplification effect in psoriasis. Macromolecule drugs targeting TNF-alpha are widely used for the clinical tr......

JIF:3.14

N-6-methyladenosine-modified long non-coding RNA AGAP2-AS1 promotes psoriasis pathogenesis via miR-424-5p/AKT3 axis

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 105 (1)

Background: Psoriasis is a chronic, complicated, and recurrent inflammatory skin disease. However, the precise molecular mechanisms remain largely elu......

JIF:3.14

TRPA1 promotes melanosome phagocytosis in keratinocytes via PAR-2/CYLD axis

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 106 (3)

Background: Keratinocytes are recipients of melanosomes. Although the chemical basis of melanogenesis is well documented, the molecular mechanism of m......

JIF:3.14

HOXA11-AS facilitates the proliferation, cell cycle process and migration of keloid fibroblasts through sponging miR-188-5p to regulate VEGFA

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 106 (2)

Background: Abnormal expression of long non-coding RNA (lncRNA) has been proved to be related to the formation of keloid. Homeobox A11 antisense (HOXA......

JIF:3.14

Yohimbine hydrochloride inhibits skin melanin synthesis by regulating wnt/beta-catenin and p38/MAPK signal pathways

期刊: JOURNAL OF DERMATOLOGICAL SCIENCE, 2022; 107 (1)

Background: Yohimbine hydrochloride (YH) is a prescription drug to treat erectile dysfunction. It also had potential in fighting high blood pressure a......

JIF:3.14

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