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Context-dependent transcriptional regulations of YAP/TAZ in stem cell and differentiation

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Hippo pathway is initially identified as a master regulator for cell proliferation and organ size control, and the subsequent researches show this pat......

JIF:5.081

Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle cerebral artery occlusion

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Background Adipose-derived stem cells (ADSCs) and their extracellular vesicles (EVs) have therapeutic potential in ischemic brain injury, but the unde......

JIF:5.081

Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Mesenchymal stem cell (MSC)-based therapy has been considered as a promising approach targeting a variety of intractable diseases due to remarkable mu......

JIF:5.081

Mesh-like electrospun membrane loaded with atorvastatin facilitates cutaneous wound healing by promoting the paracrine function of mesenchymal stem cells

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Background Functional electrospun membranes are promising dressings for promoting wound healing. However, their microstructure and drug loading capaci......

JIF:5.081

Epigenetic therapy targeting bone marrow mesenchymal stem cells for age-related bone diseases

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

As global aging accelerates, the prevention and treatment of age-related bone diseases are becoming a critical issue. In the process of senescence, bo......

JIF:5.081

Application of stem cells and exosomes in the treatment of intracerebral hemorrhage: an update

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Non-traumatic intracerebral hemorrhage is a highly destructive intracranial disease with high mortality and morbidity rates. The main risk factors for......

JIF:5.081

Cell-free fat extract improves ovarian function and fertility in mice with premature ovarian insufficiency

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Background Premature ovarian insufficiency (POI) is a refractory disease that seriously affects the reproductive health of women and is increasing in ......

JIF:5.081

RA signaling pathway combined with Wnt signaling pathway regulates human-induced pluripotent stem cells (hiPSCs) differentiation to sinus node-like cells

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Background The source of SAN is debated among researchers. Many studies have shown that RA and Wnt signaling are involved in heart development. In thi......

JIF:5.081

Efficacy of stem cell therapy in animal models of intracerebral hemorrhage: an updated meta-analysis

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Background Multiple studies have reported that stem cell therapy has beneficial effects in animal models of intracerebral hemorrhage (ICH). However, t......

JIF:5.081

TNFAIP6 defines the MSC subpopulation with enhanced immune suppression activities

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Background Mesenchymal stromal/stem cells (MSCs) have been intensively investigated in both pre-clinical and clinical studies. However, the therapeuti......

JIF:5.081

miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Background Acute spinal cord injury (SCI) is a devastating result of neurological trauma with subsequent microenvironment dyshomeostasis that induces ......

JIF:5.081

The application of mesenchymal stromal cells (MSCs) and their derivative exosome in skin wound healing: a comprehensive review

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Recently, mesenchymal stromal cells (MSCs) and also their exosome has become a game-changing tool in the context of tissue engineering and regenerativ......

JIF:5.081

Matrix vesicles from dental follicle cells improve alveolar bone regeneration via activation of the PLC/PKC/MAPK pathway

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Background The regeneration of bone loss that occurs after periodontal diseases is a significant challenge in clinical dentistry. Extracellular vesicl......

JIF:5.081

Mesenchymal Mycn participates in odontoblastic lineage commitment by regulating Kruppel-like Factor 4 (Klf4) in mice

期刊: STEM CELL RESEARCH & THERAPY, 2022; 13 (1)

Background: Commitment of mouse dental papilla cells (mDPCs) to the odontoblast lineage is critical for dentin formation, and this biological process ......

JIF:5.081

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