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Transient Inhibition of the JNK Pathway Promotes Human Hematopoietic Stem Cell Quiescence and Engraftment

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (6)

The widespread clinical application of cord blood (CB) for hematopoietic stem cell (HSC) transplantation is limited mainly by the inadequate number of......

JIF:5.607

Augmented Production of Platelets From Cord Blood With Euchromatic Histone Lysine Methyltransferase Inhibition

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (9)

Cord blood hematopoietic stem/progenitor cells (CB-HSPCs) have emerged as a promising supply for functional platelets to potentially alleviate the inc......

JIF:5.607

METTL14 Regulates Osteogenesis of Bone Marrow Mesenchymal Stem Cells via Inducing Autophagy Through m(6)A/IGF2BPs/Beclin-1 Signal Axis

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (9)

The development of osteoporosis is often accompanied by autophagy disturbance, which also causes new osteoblast defects from bone marrow mesenchymal s......

JIF:5.607

Neural Stem/Progenitor Cell Transplantation in Parkinson's Rodent Animals: A Meta-Analysis and Systematic Review

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (4)

The effects of neural stem/progenitor cells (NSPCs) have been extensively evaluated by multiple studies in animal models of Parkinson's disease (PD), ......

JIF:5.607

Periostin Attenuates Cyclophosphamide-induced Bladder Injury by Promoting Urothelial Stem Cell Proliferation and Macrophage Polarization

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (6)

Interstitial cystitis (IC) is a bladder syndrome of unclear etiology with no generally accepted treatment. Growing evidence suggest that periostin (PO......

JIF:5.607

Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Autistic-Like Behaviors of SHANK3 Mutant Beagle Dogs

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (7)

Mesenchymal stem cell-based therapy has emerged as a great potential approach to treat individuals with autism spectrum disorders (ASD), a group of de......

JIF:5.607

Intradiscal Injection of Autologous Discogenic Cells in Patients with Discectomy: A Prospective Clinical Study of Its Safety and Feasibility

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (5)

The treatment of intervertebral disc degeneration (IVDD) is still a huge challenge for clinical updated surgical techniques and basic strategies of in......

JIF:5.607

Site-Specific Integration of TRAIL in iPSC-Derived Mesenchymal Stem Cells for Targeted Cancer Therapy

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (3)

Mesenchymal stem cells (MSCs) are a promising cellular vehicle for transferring anti-cancer factors to malignant tumors. Currently, a variety of anti-......

JIF:5.607

Chemical-Empowered Human Adipose-Derived Stem Cells with Lower Immunogenicity and Enhanced Pro-angiogenic Ability Promote Fast Tissue Regeneration

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (5)

Mesenchymal stem cells (MSCs) have been widely used as functional components in tissue engineering. However, the immunogenicity and limited pro-angiog......

JIF:5.607

Rejuvenation of Tissue Stem Cells by Intrinsic and Extrinsic Factors

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (3)

Stem cell therapies, including stem cell transplantation and rejuvenation of stem cells in situ, are promising avenues for tackling a broad range of d......

JIF:5.607

Mesenchymal Stem/Stromal Cell Senescence: Hallmarks, Mechanisms, and Combating Strategies

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (4)

Aging is a multifaceted and complicated process, manifested by a decline of normal physiological functions across tissues and organs, leading to overt......

JIF:5.607

Clinical Progress and Preclinical Insights Into Umbilical Cord Blood Transplantation Improvement

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (9)

The application of umbilical cord blood (UCB) as an important source of hematopoietic stem and progenitor cells (HSPCs) for hematopoietic reconstituti......

JIF:5.607

Stem Cell Therapies for Chronic Liver Diseases: Progress and Challenges

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (9)

Chronic liver diseases have become a significant health issue worldwide and urgently require the development of novel therapeutic approaches, in addit......

JIF:5.607

Autologous Stem Cells Transplantation for No-Option Angiitis-Induced Critical Limb Ischemia: Recurrence and New Lesion

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (5)

Although satisfying outcomes have been demonstrated in terms of autologous stem cell transplantation in the treatment of angiitis-induced critical lim......

JIF:5.607

Neural Stem Cell-Derived Exosomal Netrin1 Contributes to Neuron Differentiation of Mesenchymal Stem Cells in Therapy of Spinal Bifida Aperta

期刊: STEM CELLS TRANSLATIONAL MEDICINE, 2022; 11 (5)

Spinal bifida aperta (SBA) is a congenital malformation with a high incidence. Bone marrow mesenchymal stem cell (BMSC) transplantation has the potent......

JIF:5.607

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