期刊: PLOS BIOLOGY, 2022; 20 (2)
Elevated circulating levels of growth differentiation factor 15 (GDF15) have been shown to reduce food intake and lower body weight through activation......
期刊: PLOS BIOLOGY, 2022; 20 (3)
Hemispheric lateralization constitutes a core architectural principle of human brain organization underlying cognition, often argued to represent a st......
期刊: PLOS BIOLOGY, 2022; 20 (6)
In contrast to the adult mammalian central nervous system (CNS), the neurons in the peripheral nervous system (PNS) can regenerate their axons. Howeve......
期刊: PLOS BIOLOGY, 2022; 20 (4)
Skeletal muscle regeneration is essential for maintaining muscle function in injury and muscular disease. Myogenesis plays key roles in forming new my......
期刊: PLOS BIOLOGY, 2022; 20 (1)
Lipid droplets (LDs) have increasingly been recognized as an essential organelle for eukaryotes. Although the biochemistry of lipid synthesis and degr......
期刊: PLOS BIOLOGY, 2022; 20 (5)
Metacognition and mentalizing are both associated with meta-level mental state representations. Conventionally, metacognition refers to monitoring one......
期刊: PLOS BIOLOGY, 2022; 20 (8)
Mitochondrial DNA (mtDNA) mutations are often associated with incurable diseases and lead to detectable pathogenic variants in 1 out of 200 babies. Un......
期刊: PLOS BIOLOGY, 2021; 19 (4)
Renal cell carcinoma (RCC) is responsible for most cases of the kidney cancer. Previous research showed that low serum levels of cholesterol level pos......
期刊: PLOS BIOLOGY, 2021; 19 (8)
Pathogenic fungi precisely respond to dynamic microenvironments during infection, but the underlying mechanisms are not well understood. The insect pa......
期刊: PLOS BIOLOGY, 2021; 19 (8)
Tumor necrosis factor receptor-1 (TNFR1) signaling, apart from its pleiotropic functions in inflammation, plays a role in embryogenesis as deficiency ......
期刊: PLOS BIOLOGY, 2021; 19 (8)
Beige fat dissipates energy and functions as a defense against cold and obesity, but the mechanism for its development is unclear. We found that inter......
期刊: PLOS BIOLOGY, 2021; 19 (7)
Peripheral nerve injury-induced mechanical allodynia is often accompanied by abnormalities in the higher cortical regions, yet the mechanisms underlyi......
期刊: PLOS BIOLOGY, 2021; 19 (4)
MgtE is a Mg2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg2+ homeostasi......
期刊: PLOS BIOLOGY, 2021; 19 (6)
Little is known about mechanisms of membrane fission in bacteria despite their requirement for cytokinesis. The only known dedicated membrane fission ......
期刊: PLOS BIOLOGY, 2021; 19 (7)
Synaptotagmin-7 (Syt7) plays direct or redundant Ca2+ sensor roles in multiple forms of vesicle exocytosis in synapses. Here, we show that Syt7 is a r......