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miR-122-5p targets GREM2 to protect against glucocorticoid-induced endothelial damage through the BMP signaling pathway

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 544 ()

Glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH) accounts for a big portion of non traumatic ONFH; nevertheless, the pathogenesis ......

JIF:3.76

Autophagy protects against high uric acid-induced hepatic insulin resistance

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 547 ()

Uric acid (UA), the end-product of purine metabolism, is closely related to hepatic insulin resistance (IR). Autophagy is a conserved intracellular de......

JIF:3.76

FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 540 ()

Although the follicle-stimulating hormone (FSH) plays a vital role in male reproduction, the molecular relationships among FSH, autophagy, and the sec......

JIF:3.76

Tanshinone IIA and its derivative activate thermogenesis in adipocytes and induce beiging of white adipose tissue

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 544 ()

Tanshinone IIA (TAN2A) is a major active ingredient of Salvia miltiorrhiza used in traditional Chinese medicine and tanshinone 20 (TAN20) is a derivat......

JIF:3.76

Combinational exposure to Bisphenol A and a high-fat diet causes trans-generational Malfunction of the female reproductive system in mice

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 541 ()

Bisphenol A (BPA) is a common endocrine disruptor and a high-fat diet (HFD) also affects fertility. However, little is known about the long-term conse......

JIF:3.76

Treatment with spexin mitigates diet-induced hepatic steatosis in vivo and in vitro through activation of galanin receptor 2

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 552 ()

It was reported that spexin as an adipocyte-secreted protein could regulate obesity and insulin resistance. However, the specific metabolic contributi......

JIF:3.76

Tripartite motif containing 63, regulated by E26 transformation specific variant 4, facilitates the thyroid carcinoma progression and the AKT, p38, and ERK signaling pathways

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 550 ()

The current study aimed to investigate the role of tripartite motif containing 63 (TRIM63) in the progression of thyroid carcinomas. The results showe......

JIF:3.76

Elevated latent transforming growth factor beta binding protein 2 in endometriosis promotes endometrial stromal cell invasion and proliferation via the NF-kB signaling pathway

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 550 ()

Endometriosis, defined as the abnormal growth of functional endometrium outside the uterus, is characterized by the abnormal phenotype of endometrial ......

JIF:3.76

Smtnl2 regulates apoptotic germ cell clearance and lactate metabolism in mouse Sertoli cells

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 551 ()

Smtnl2 is an epithelial Smoothelin that binds to actin filaments and is crucial for epithelial morphogenesis. We examined the role of Smtnl2 in Sertol......

JIF:3.76

Study of differential proteomics in granulosa cells of premature ovarian insufficiency (POI) and the roles and mechanism of RAC1 in granulosa cells

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 555 ()

In the present study, we focused on characterizing the proteome in granulosa cells in patients with biochemical premature ovarian insufficiency (bPOI)......

JIF:3.76

TLR4 inhibition ameliorated glucolipotoxicity-induced differentiation suppression in osteoblasts via RIAM regulation of NF-kappa B nuclear translocation

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 543 ()

TLR4 is a key innate immune signal that mediates glucolipid toxicity through yet unclear mechanisms. Here, TLR4 truncation ameliorated bone metabolism......

JIF:3.76

Liraglutide prevents high glucose induced HUVECs dysfunction via inhibition of PINK1/Parkin-dependent mitophagy

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 545 ()

Functional loss of endothelial cells will lead to development and progression of atherosclerosis in diabetic patients. However, dysfunction of endothe......

JIF:3.76

Pleiotropic roles of FXR in liver and colorectal cancers

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 543 ()

Nuclear receptor farnesoid X receptor (FXR) is generally considered a cell protector of enterohepatic tissues and a suppressor of liver cancer and col......

JIF:3.76

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