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Monalbidins A-E, Decalins with Potential Cytotoxic Activities from Marine Derived Fungus Monascus albidus BB3

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (5)

Five new decalins, monalbidins A-E (1, 2 and 7-9), together with 16 known compounds (3-6 and 10-21), were isolated from the AcOEt extract of marine de......

Tetranorlanostane and Lanostane Triterpenoids with Cytotoxic Activity from the Epidermis of Poria cocos

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (5)

Two unprecedented tetranorlanostane triterpenoids, poricolides A (1) and B (2), and two new lanostane triterpenoids, 3 beta-acetoxy-24-methyllanosta-8......

Antifungal Biphenyl Derivatives from Sorbus pohuashanensis Leaves Infected by Alternaria tenuissi and Their Effect against Crop Pathogens

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (5)

Eight natural biphenyl-type phytoalexins exhibiting antifungal effect were isolated from the leaves of Sorbus pohuashanensis, which invaded by Alterna......

Total Flavonoids of Engelhardia roxburghiana Wall. Leaves Alleviated Foam Cells Formation through AKT/mTOR-Mediated Autophagy in the Progression of Atherosclerosis

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (9)

Engelhardia roxburghiana Wall. is a traditional Chinese medicine used for treating cardiovascular diseases. Our previous study has implicated potentia......

Commiphoranes K-O, New Terpenoids from Resina Commiphora and Their Anti-Inflammatory Activities

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (7)

Commiphorane K (1), a new dinorditerpenoid, commiphoranes L-N (2-4), three new germacrane-type sesquiterpenoids, and commiphorane O (5), one new guaia......

Synthesis and Anti-Oomycete Activity of 1-Sulfonyloxy/Acyloxydihydroeugenol Derivatives

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (9)

Endeavor to discover biorational natural products-based fungicides, two series (26) of novel 1-sulfonyloxy/acyloxydihydroeugenol derivatives (3a-p and......

Chemically Sulfated Polysaccharides from Agaricus blazei Murill: Synthesis, Characterization and Anti-HIV Activity

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (9)

AIDS, caused by HIV-1, is one of the most dangerous infectious diseases in the world. Therefore, it is necessary to develop new drugs with more potent......

Shengxuening Extracted from Silkworm Excrement Mitigates Myelosuppression via SCF-Mediated JAK2/STAT3 Signaling

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (6)

Shengxuening (SXN) is a Chinese patent medicine with main ingredients (including chlorophyll derivatives and sodium iron chlorophyllin) extracted from......

Exploring the Potential Mechanism of Costunolide-Induced MCF-7 Cells Apoptosis by Multi-Spectroscopy, Molecular Docking and Cell Experiments

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (5)

Breast cancer is one of the most common cancer with high morbidity and mortality in women. This study aimed to explore the potential mechanism of cost......

Natural Triterpenoids Isolated from Akebia trifoliata Stem Explants Exert a Hypoglycemic Effect via alpha-Glucosidase Inhibition and Glucose Uptake Stimulation in Insulin-Resistant HepG2 Cells

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (5)

The inhibition of alpha-glucosidase activity is a prospective approach to attenuate postprandial hyperglycemia in the treatment of type 2 diabetes mel......

Neuroprotective Activities of Constituents from Phyllosticta capitalensis, an Endophyte Fungus of Loropetalum chinense var. rubrum

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (8)

One new dioxolanone derivative, guignardianone G (1) and twelve known compounds (2-13) were isolated from the 95 % ethanol extract of the plant endoph......

Cloning and Functional Characterization of a Squalene Synthase from Paris polyphylla var. yunnanensis

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (7)

Paris polyphylla Smith var. yunnanensis (Franch.) Hand. - Mazz. is a precious traditional Chinese medicine, and steroidal saponins are its major bioac......

Five New Triene Derivatives from the Fungus Penicillium herquei JX4

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (5)

Five undescribed triene derivatives, pinophols B-F (2-6), together with one known compound, pinophol A (1), were obtained from the mangrove endophytic......

Protective Effect of n-Butanol Extract from Viola yedoensis on Immunological Liver Injury

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (6)

Viola yedoensis Makino was used to treat inflammation, viral hepatitis, acute pyogenic infection, and ulcerative carbuncles. However, the protective e......

Discovery of 4,6-Disubstituted Pyrimidine Derivatives as Novel Dual VEGFR2/FGFR1 Inhibitors

期刊: CHEMISTRY & BIODIVERSITY, 2021; 18 (5)

Abnormalities in the FGFRs signaling pathway and VEGFR2 amplification often occur in a variety of tumors, and they synergistically promote tumor angio......

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