期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
The hypoxic microenvironment contributes to the chemoresistance of many malignant tumors including colorectal cancer (CRC). Accumulating studies have ......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
Regulation of alternative splicing (AS) by the splicing factor 3b (SF3B) family plays an essential role in cancer. However, the biological function of......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
We commenced to analyze putative anti-pyroptosis effects of puerarin (PU) as mediated by the PP2A-HDAC1-NLRP3 pathway in acute lung injury (ALI). ALI ......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
Acute kidney injury (AKI) is in high prevalence in the world. However, the therapeutic strategies for AKI are still in mystery. Studies have shown to ......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
Colorectal cancer (CRC) is one of the digestive tract malignancies whose early symptoms are not obvious. This study aimed to identify novel targets fo......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
Neonatal brain hypoxic ischemic injury is a devastating event causing permanent brain damage. The current study set out to explore the role of Kruppel......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
Sphingosine kinase 1 (SphK1) expression and activity are elevated in human osteosarcoma (OS) and is a promising target of therapy. SKI-V is a non-comp......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
The hippocampal neurogenesis occurs constitutively throughout adulthood in mammalian species, but declines with age. In this study, we overtly found t......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
Moderate autophagy can remove damaged proteins and organelles. In some inflammatory diseases, autophagy plays a protective role by inhibiting the NOD-......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
The fat mass and obesity-associated protein (FTO) is an N6-Methyladenosine (m6A) demethylase, which has been revealed to play critical roles in tumori......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
Recent evidence indicates that exosomes derived from mesenchymal stem cells (MSCs) confer protective effects against myocardial ischemia/reperfusion (......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
Lymph node (LN) metastasis is associated with unfavorable prognosis of bladder cancer (BCa). Although lymphangiogenesis is functionally important in L......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
T-cell acute lymphoblastic leukemia (T-ALL) is a type of leukemia with high malignant behaviors, which seriously threatens the health of people. It ha......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
Bacillus cereus is well known as a causative agent of foodborne gastrointestinal diseases and systemic non-gastrointestinal diseases. We have recently......
期刊: CELL DEATH DISCOVERY, 2022; 8 (1)
The phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway plays an essential role in glucose metabolism, promoting glycolysis and resisting gluco......