期刊: CELL STEM CELL, 2022; 29 (7)
H3K9me3, as a hallmark of heterochromatin, is important for cell-fate specification. However, it remains un-known how H3K9me3 is reprogrammed during h......
期刊: CELL STEM CELL, 2022; 29 (4)
Region-related heterogeneity and state transitions of microglia are important for brain development and neurological pathogenesis. However, regional s......
期刊: CELL STEM CELL, 2022; 29 (4)
Zebrafish and mammalian neonates possess robust cardiac regeneration via the induction of endogenous cardiomyocyte (CM) proliferation, but adult mamma......
期刊: CELL STEM CELL, 2022; 29 (6)
2-cell-like cells (2CLCs)-which comprise only similar to 1% of murine embryonic stem cells (mESCs)-resemble blastomeres of 2-cell-stage embryos and ar......
期刊: CELL STEM CELL, 2022; 29 (1)
N-6-methyladenosine (m(6)A) on mRNA plays critical roles in various cellular processes. However, the landscape and dynamics of m(6)A modification in h......
期刊: CELL STEM CELL, 2022; 29 (3)
Totipotent cells have more robust developmental potency than any other cell types, giving rise to both embryonic and extraembryonic tissues. Stable to......
期刊: CELL STEM CELL, 2022; 29 (11)
The communication between glioblastoma stem cells (GSCs) and the surrounding microenvironment is a prominent feature accounting for the aggressive bio......
期刊: CELL STEM CELL, 2022; 29 (8)
Reprogramming somatic cells into megakaryocytes (MKs) would provide a promising source of platelets. However, using a pharmacological approach to gene......
期刊: CELL STEM CELL, 2022; 29 (11)
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue regeneration and homeostasis. In-vitro-expanded MSCs are e......
期刊: CELL STEM CELL, 2022; 29 (7)
Reprogramming of H3K9me3-dependent heterochromatin is required for early development. How H3K9me3 is involved in early human development remains, howe......
期刊: CELL STEM CELL, 2022; 29 (6)
The young circulatory milieu capable of delaying aging in individual tissues is of interest as rejuvenation strategies, but how it achieves cellular-a......
期刊: CELL STEM CELL, 2022; 29 (7)
Hematopoietic stem cells (HSCs) adapt their metabolism to maintenance and proliferation; however, the mechanism remains incompletely understood. Here,......
期刊: CELL STEM CELL, 2022; 29 (11)
During fetal development, human hematopoietic stem cells (HSCs) colonize the bone marrow (BM), where they self-renew and sustain hematopoiesis through......
期刊: CELL STEM CELL, 2022; 29 (9)
Although disrupted bile acid (BA) homeostasis is implicated in inflammatory bowel disease (IBD), the role of hepatic BA metabolism in the pathogenesis......
期刊: CELL STEM CELL, 2022; 29 (2)
The hypothalamus comprises various nuclei and neuronal subpopulations that control fundamental homeostasis and behaviors. However, spatiotemporal mole......