期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (8)
Background Slit diaphragm is a specialized adhesion junction between the opposing podocytes, establishing the final filtration barrier to urinary prot......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (6)
Background Transcriptional programs control cell fate, and identifying their components is critical for under-standing diseases caused by cell lesion,......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (8)
Background Antiglomerular basement membrane (anti-GBM) disease is characterized byGNand often pulmonary hemorrhage, mediated by autoantibodies that ty......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (8)
Background Bilateral renal agenesis (BRA) is a lethal con genital anomaly caused by the failure of normal development of both kidneys early in embryon......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (2)
Background Fine particulate matter (PM2.5) is an important environmental risk factor for cardiopulmonary diseases. However, the association between PM......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (2)
Background On the basis of findings of observational studies and a meta-analysis, proteinuria reduction has been proposed as a surrogate outcome in Ig......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (3)
Background Potassium levels regulate multiple physiologic processes. The heritability of serum potassium level is moderate, with published estimates v......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (3)
Background Kidney function declines faster in men. Testosterone levels may mediate the sex disparity. Correspondingly, levels of sex hormone binding g......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (3)
Background Galactose-deficient IgA1 plays a key role in the pathogenesis of IgA nephropathy, the most common primary GN worldwide. Although serum leve......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (1)
Background Despite increasing incidence of CKD, no evidence-based lifestyle recommendations for CKD primary prevention apparently exist. Methods To ev......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021; 32 (1)
Significance Statement Aberrantly upregulated cell proliferation in kidney tubule cyst cells promotes cyst progression in autosomal dominant polycysti......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2022; 33 (12)
Background Gut dysbiosis is postulated to participate in the pathogenesis of IgA nephropathy (IgAN). However, the key bacterial taxa closely associate......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2022; 33 (12)
Background The kidneys critically contribute to body homeostasis under the control of the autonomic nerves, which enter the kidney along the renal vas......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2022; 33 (9)
Background The complement system is highly activated in primary membranous nephropathy (MN). Iden-tifying the complement components that damage podocy......