Menin-regulated Pbk controls high fat diet-induced compensatory beta cell proliferation

Ma, J; Xing, BW; Cao, Y; He, X; Bennett, KE; Tong, C; An, CY; Hojnacki, T; Feng, ZJ; Deng, SB; Ling, SB; Xie, GC; Wu, Y; Ren, Y; Yu, M; Katona, BW; Li, HZ; Naji, A; Hua, XX

Hua, XX (corresponding author), Univ Penn, Perelman Sch Med, Abramson Family Canc Res Inst, Dept Canc Biol, Philadelphia, PA 19104 USA.; Hua, XX (corresponding author), Univ Penn, Perelman Sch Med, Inst Diabet Obes & Metab, Philadelphia, PA 19104 USA.

EMBO MOLECULAR MEDICINE, 2021; 13 (5):

Abstract

Pancreatic beta cells undergo compensatory proliferation in the early phase of type 2 diabetes. While pathways such as FoxM1 are involved in regulatin......

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