Systematic prediction of degrons and E3 ubiquitin ligase binding via deep learning

Hou, C; Li, YX; Wang, MY; Wu, H; Li, TT

Li, TT (通讯作者),Peking Univ, Hlth Sci Ctr, Sch Basic Med Sci, Dept Biomed Informat, Beijing 100191, Peoples R China.

BMC BIOLOGY, 2022; 20 (1):

Abstract

Background: Degrons are short linear motifs, bound by E3 ubiquitin ligase to target protein substrates to be degraded by the ubiquitin-proteasome syst......

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