ATP6AP2 knockdown in cardiomyocyte deteriorates heart function via compromising autophagic flux and NLRP3 inflammasome activation

Li, L; Cui, YJ; Liu, Y; Li, HX; Su, YD; Li, SN; Wang, LL; Zhao, YW; Wang, SX; Yan, F; Dong, B

Dong, B (通讯作者)，Shandong Univ, Shandong Prov Hosp, Cheeloo Coll Med, Dept Cardiol, Jinan 250012, Peoples R China.;Yan, F (通讯作者)，Shandong Univ, Qilu Hosp, Cheeloo Coll Med,Key Lab Cardiovasc Remodeling &, Dept Cardiol,Chinese Minist Educ,Chinese Natl Hlt, Jinan 250012, Peoples R China.;Yan, F (通讯作者)，Shandong Univ, Qilu Hosp, Cheeloo Coll Med, Dept Cardiol,Chinese Acad Med Sci,State & Shandon, Jinan 250012, Peoples R China.;Dong, B (通讯作者)，Shandong First Med Univ & Shandong Acad Med Sci, Shandong Pr

CELL DEATH DISCOVERY, 2022; 8 (1):

Abstract

Moderate autophagy can remove damaged proteins and organelles. In some inflammatory diseases, autophagy plays a protective role by inhibiting the NOD-......

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