Paracrine IGF-1 Activates SOD2 Expression and Regulates ROS/p53 Axis in the Treatment of Cardiac Damage in D-Galactose-Induced Aging Rats after Receiving Mesenchymal Stem Cells

Hu, WS; Liao, WY; Chang, CH; Chen, TS

Chang, CH (通讯作者),Chu Kong Hosp, Tradit Chinese Med Dept, New Taipei 40237, Taiwan.;Chang, CH (通讯作者),Chang Gung Univ Sci & Technol, Dept Cosmet Sci, Taoyuan 33303, Taiwan.;Chang, CH (通讯作者),China Med Univ, Coll Chinese Med, Taichung 40402, Taiwan.;Chen, TS (通讯作者),Natl Taiwan Normal Univ, Grad Program Biotechnol & Pharmaceut Ind, Taipei 11677, Taiwan.

JOURNAL OF CLINICAL MEDICINE, 2022; 11 (15):

Abstract

Aging is one of the causative agents associated with heart failure. Cell-based therapies show potential in the treatment of cardiac aging due to the c......

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