Multisystem inflammation and susceptibility to viral infections in human ZNFX1 deficiency

Vavassori, S; Chou, JE; Faletti, LE; Haunerdinger, V; Opitz, L; Joset, P; Fraser, CJ; Prader, S; Gao, XF; Schuch, LA; Wagner, M; Hoefele, J; Maccari, ME; Zhu, Y; Elakis, G; Gabbett, MT; Forstner, M; Omran, H; Kaiser, T; Kessler, C; Olbrich, H; Frosk, P; Almutairi, A; Platt, CD; Elkins, M; Weeks, S; Rubin, T; Planas, R; Marchetti, T; Koovely, D; Klambt, V; Soliman, NA; von Hardenberg, S; Klemann, C; Baumann, U; Lenz, D; Klein-Franke, A; Schwemmle, M; Huber, M; Sturm, E; Hartleif, S; Haaffner, K; Gimpel, C; Brotschi, B; Laube, G; Gungor, T; Buckley, MF; Kottke, R; Staufner, C; Hildebrandt, F; Reu-Hofer, S; Moll, S; Weber, A; Kaur, H; Ehl, S; Hiller, S; Geha, R; Roscioli, T; Griese, M; Schmid, JP

Schmid, JP (corresponding author), Univ Childrens Hosp Zurich, Div Immunol, Steinwiesstr 75, CH-8032 Zurich, Switzerland.; Geha, R (corresponding author), Harvard Med Sch, Boston Childrens Hosp, Div Immunol, 300 Longwood Ave, Boston, MA 02115 USA.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2021; 148 (2): 381

Abstract

Background: Recognition of viral nucleic acids is one of the primary triggers for a type I interferon-mediated antiviral immune response. Inborn error......

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