The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer

Yang, X; Cruz, MI; Nguyen, EV; Huang, C; Schittenhelm, RB; Luu, J; Cowley, KJ; Shin, SY; Nguyen, LK; Sian, TCCLK; Clark, KC; Simpson, KJ; Ma, XQ; Daly, RJ

Daly, RJ (通讯作者)，Monash Univ, Biomed Discovery Inst, Canc Program, Melbourne, VIC 3800, Australia.;Daly, RJ (通讯作者)，Monash Univ, Dept Biochem & Mol Biol, Melbourne, VIC 3800, Australia.

ONCOGENE, 2023; 42 (11): 833

Abstract

We have determined that expression of the pseudokinase NRBP1 positively associates with poor prognosis in triple negative breast cancer (TNBC) and is ......

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