OTUD1 Regulates Antifungal Innate Immunity through Deubiquitination of CARD9

Chen, XR; Zhang, HH; Wang, XE; Shao, ZG; Li, YQ; Zhao, GM; Liu, F; Liu, BY; Zheng, Y; Chen, T; Zheng, H; Zhang, L; Gao, CJ

Zhang, L; Gao, CJ (corresponding author), Shandong Univ, Sch Biomed Sci, Dept Immunol, Jinan 250012, Shandong, Peoples R China.; Zheng, H (corresponding author), Soochow Univ, Int Inst Infect & Immun, Inst Biol, Suzhou 215123, Jiangsu, Peoples R China.; Zheng, H (corresponding author), Soochow Univ, Int Inst Infect & Immun, Inst Med Sci, Suzhou 215123, Jiangsu, Peoples R China.

JOURNAL OF IMMUNOLOGY, 2021; 206 (8): 1832

Abstract

CARD9 is an essential adaptor protein in antifungal innate immunity mediated by C-type lectin receptors. The activity of CARD9 is critically regulated......

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