Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2S production

Wang, WY; Ren, SF; Lu, YK; Chen, X; Qu, JJ; Ma, XJ; Deng, Q; Hu, ZS; Jin, Y; Zhou, ZY; Ge, WY; Zhu, YB; Yang, NN; Li, Q; Pu, JQ; Chen, G; Ye, CQ; Wang, H; Zhao, XY; Liu, ZQ; Zhu, SY

Zhu, SY (corresponding author), Zhejiang Univ, MOE Key Lab Biosyst Homeostasis & Protect, Life Sci Inst, Hangzhou, Peoples R China.; Zhu, SY (corresponding author), Zhejiang Univ, Zhejiang Prov Key Lab Canc Mol Cell Biol, Life Sci Inst, Hangzhou, Peoples R China.; Zhu, SY (corresponding author), Zhejiang Univ, Sch Med, Affiliated Hosp 2, Hangzhou, Peoples R China.

EMBO JOURNAL, 2021; 40 (11):

Abstract

Chemical compounds have recently been introduced as alternative and non-integrating inducers of pluripotent stem cell fate. However, chemical reprogra......

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