Ribonucleotide reductase M2 subunit silencing suppresses tumorigenesis in pancreatic cancer via inactivation of PI3K/AKT/mTOR pathway

Shan, JL; Wang, Z; Mo, QP; Long, JP; Fan, YF; Cheng, L; Zhang, T; Liu, XY; Wang, XC

Wang, XC (通讯作者)，Zhejiang Univ, Sch Med, Dept Breast Surg & Oncol, Affiliated Hosp 2, 88 Jiefang Rd, Hangzhou 310009, Zhejiang, Peoples R China.

PANCREATOLOGY, 2022; 22 (3): 401

Abstract

Background/objectives: Ribonucleotide Reductase M2 subunit (RRM2) is elevated in pancreatic cancer and involved in DNA synthesis and cell proliferatio......

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