Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer

Qiu, YF; Yang, Y; Yang, RY; Liu, CX; Hsu, JM; Jiang, Z; Sun, LL; Wei, YK; Li, CW; Yu, DH; Zhang, J; Hung, MC

Zhang, J (corresponding author), Tianjin Med Univ Canc Inst & Hosp, Treatment & Res Ctr, Dept Breast Canc Prevent 3, Tianjin, Peoples R China.; Zhang, J (corresponding author), Tianjin Med Univ Canc Inst & Hosp, Minist Educ, Key Lab Breast Canc Prevent & Therapy, Tianjin, Peoples R China.; Zhang, J (corresponding author), Tianjin Med Univ Canc Inst & Hosp, Tianjins Clin Res Ctr Canc, Tianjin, Peoples R China.; Zhang, J (corresponding author), Tianjin Med Univ Canc Inst & Hosp, Key Lab Canc Preve

ONCOGENE, 2021; 40 (31): 4992

Abstract

Programmed cell death 1 (PD-1) is widely expressed in tumor-infiltrating lymphocytes (TILs) of triple-negative breast cancer (TNBC). As a dominant inh......

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