Platelet-Derived TGF (Transforming Growth Factor)-beta 1 Enhances the Aerobic Glycolysis of Pulmonary Arterial Smooth Muscle Cells by PKM2 (Pyruvate Kinase Muscle Isoform 2) Upregulation

Zhu, Y; Shu, D; Gong, X; Lu, M; Feng, QY; Zeng, XB; Zhang, H; Gao, JH; Guo, YW; Liu, LM; Ma, R; Zhu, LP; Hu, QH; Ming, ZY

Ming, ZY (通讯作者)，HUST, Sch Basic Med, Dept Pharmacol, Tongji Med Coll, 13 Hangkong Rd, Wuhan, Hubei, Peoples R China.

HYPERTENSION, 2022; 79 (5): 932

Abstract

Background: Metabolic reprogramming is a hallmark of pulmonary arterial hypertension. Platelet activation has been implicated in pulmonary arterial hy......

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