A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea

Deng, ZL; Chen, MT; Liu, YZ; Xu, S; Ouyang, YY; Shi, W; Jian, D; Wang, B; Liu, FF; Li, JM; Shi, Q; Peng, QQ; Sha, K; Xiao, WQ; Liu, TX; Zhang, YY; Zhang, HB; Wang, Q; Sun, LQ; Xie, HF; Li, J

Li, J (corresponding author), Cent South Univ, Xiangya Hosp, Dept Dermatol, Changsha, Peoples R China.; Li, J (corresponding author), Cent South Univ, Xiangya Hosp, Hunan Key Lab Aging Biol, Changsha, Peoples R China.; Li, J (corresponding author), Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha, Peoples R China.; Li, J (corresponding author), Key Lab Mol Radiat Oncol Hunan Prov, Changsha, Peoples R China.; Li, J (corresponding author), Cent South Univ, Key Lab Organ

EMBO MOLECULAR MEDICINE, 2021; 13 (5):

Abstract

Rosacea is a chronic inflammatory skin disorder whose pathogenesis is unclear. Here, several lines of evidence were provided to demonstrate that mTORC......

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