Regulation of Anion Channel LRRC8 Volume-Regulated Anion Channels in Transport of 2 ' 3 '-Cyclic GMP-AMP and Cisplatin under Steady State and Inflammation

Chen, X; Wang, L; Cao, LM; Li, TT; Li, ZH; Sun, YM; Ding, JQ; Zhou, C; Xie, YD; Yue, N; Nan, J; Jia, XM; Peng, C; Li, HB; Yang, JB; Xiao, H

Xiao, H (corresponding author), Chinese Acad Sci, Inst Pasteur Shanghai, 320 Yueyang Rd,Life Sci Res Bldg B-211, Shanghai 200031, Peoples R China.; Yang, JB (corresponding author), Lanzhou Univ, Sch Life Sci, 222 South Tianshui Rd,Tianyan Bldg, Lanzhou 730000, Gansu, Peoples R China.

JOURNAL OF IMMUNOLOGY, 2021; 206 (9): 2061

Abstract

The recently identified anion channel LRRC8 volume-regulated anion channels (VRACs) are heteromeric hexamers constituted with the obligate LRRC8A subu......

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