Targeting the Erk1/2 and autophagy signaling easily improved the neurobalst differentiation and cognitive function after young transient forebrain ischemia compared to old gerbils

Wang, FX; Xia, ZH; Sheng, P; Ren, Y; Liu, JJ; Ding, LD; Yan, BC

Yan, BC (通讯作者),Yangzhou Univ, Med Coll,Key Lab Syndrome Differentiat & Treatmen, Inst Translat Med,Jiangsu Key Lab Integrated Trad, Dept Neurol,Affiliated Hosp Yangzhou Univ, Yangzhou 225001, Jiangsu, Peoples R China.;Yan, BC (通讯作者),Jiangsu Coinnovat Ctr Prevent & Control Important, Jiangsu Key Lab Zoonosis, Yangzhou 225009, Jiangsu, Peoples R China.;Yan, BC (通讯作者),Taizhou Second Peoples Hosp, Dept Neurol, Taizhou 225500, Peoples R China.

CELL DEATH DISCOVERY, 2022; 8 (1):

Abstract

The hippocampal neurogenesis occurs constitutively throughout adulthood in mammalian species, but declines with age. In this study, we overtly found t......

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