Pharmacokinetics and Molecular Modeling Indicate nAChR alpha 4-Derived Peptide HAEE Goes through the Blood-Brain Barrier

Zolotarev, YA; Mitkevich, VA; Shram, SI; Adzhubei, AA; Tolstova, AP; Talibov, OB; Dadayan, AK; Myasoyedov, NF; Makarov, AA; Kozin, SA

Kozin, SA (corresponding author), Russian Acad Sci, Engelhardt Inst Mol Biol, Lab Prot Conformat Polymorphism Hlth & Dis, Moscow 119991, Russia.

BIOMOLECULES, 2021; 11 (6):

Abstract

One of the treatment strategies for Alzheimer's disease (AD) is based on the use of pharmacological agents capable of binding to beta-amyloid (A beta)......

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