HOTAIR/miR-1277-5p/ZEB1 axis mediates hypoxia-induced oxaliplatin resistance via regulating epithelial-mesenchymal transition in colorectal cancer

Weng, XY; Liu, H; Ruan, J; Du, MY; Wang, LJ; Mao, JY; Cai, Y; Lu, XM; Chen, W; Huang, YQ; Zhi, X; Shan, JZ

Shan, JZ (通讯作者)，Zhejiang Univ, Sch Med, Affiliated Hosp 1, Dept Med Oncol, Hangzhou, Peoples R China.;Zhi, X (通讯作者)，Zhejiang Univ, Sch Med, Affiliated Hosp 1, Dept Hepatobiliary & Pancreat Surg, Hangzhou, Peoples R China.

CELL DEATH DISCOVERY, 2022; 8 (1):

Abstract

The hypoxic microenvironment contributes to the chemoresistance of many malignant tumors including colorectal cancer (CRC). Accumulating studies have ......

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