Protective Effects of Sacubitril/Valsartan on Cardiac Fibrosis and Function in Rats With Experimental Myocardial Infarction Involves Inhibition of Collagen Synthesis by Myocardial Fibroblasts Through Downregulating TGF-beta 1/Smads Pathway

Wu, MF; Guo, YG; Wu, Y; Xu, KZ; Lin, LM

Xu, KZ; Lin, LM (corresponding author), Southern Med Univ, Putian Univ, Affiliated Hosp, Dept Cardiol, Putian, Peoples R China.

FRONTIERS IN PHARMACOLOGY, 2021; 12 ():

Abstract

Objectives: To investigate the effect and mechanism of sacubitril/valsartan on myocardial fibrosis in rats following experimental myocardial infarctio......

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